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http://www.crcpress.com/product/isbn/9781420093285

(The Algebra of Organic Synthesis)

Note:  Books purchased between September 2011 and December 2011 from the publisher, online vendor, or a bookstore have a faulty CD which does not contain the correct files corresponding to the synthesis database advertised.  Please contact your vendor to obtain a replacement CD free of charge if this problem applies to your purchase.  The publisher has rectified the problem for future sales of the book as of January 2012.

 

http://www.crcpress.com/product/isbn/9781439840764

(Green Organic Chemistry in Lecture and Laboratory)

 

Book Chapters:

 

J. Andraos*, Designing a Green Organic Chemistry Lecture Course in Green Organic Chemistry in Lecture and Laboratory, (A.P. Dicks, ed.), Taylor & Francis:  Boca Raton, 2012, Chapter 2, pp. 29 - 68.

J. Andraos*, Application of Green Metrics to Scalable Industrial Synthesis Plans:  An Update on Syntheses of Oseltamivir Phosphate (Tamiflu) in Scalable Green Chemistry:  Case Studies from the Pharmaceutical Industry, (S.G. Koenig, ed.), Pan Stanford Publishing, forthcoming 2012.

J. Andraos*, Green Chemistry Metrics:  Material Efficiency and Strategic Synthesis Design in Encyclopedia of Sustainability Science and Technology, (P.T. Anastas, J. Zimmerman, eds.), Springer-Verlag:  New York, 2011.

J. Andraos*, Parameterization and Tracking of Optimization of Synthesis Strategy Using Computer Spreadsheet Algorithms in Handbook of Green Chemistry – Green Solvents (P.T. Anastas, C.J. Li, eds.), Wiley-VCH:  Weinheim, accepted.  

J. Andraos*, Atom Economy, Reaction Mass Efficiency, and E-factor Green Metrics for Gauging Material Efficiencies of Reactions and Synthesis Plans:  Paradigms and Examples in The Oxford Handbook of Green Chemistry, (W.M. Nelson, ed.), Oxford University Press:  New York, forthcoming 2013.

J. Andraos*, Application of Green Metrics Analysis to Chemical Reactions and Synthesis Plans, in Green Chemistry Metrics in Green Chemistry Metrics, (Alexei Lapkin, David C. Constable, eds.), Blackwell Scientific:  Oxford, 2008.  Chapter 4, pp. 69 - 199.

 

Publications:

 

J. Andraos*; A.P. Dicks*, Green Chemistry Teaching in Higher Education: A Review of Effective Practices, Chem. Educ. Res. Pract., 2012.

 

J. Andraos*, A Green Metrics Assessment of Phosgene and Phosgene-free Syntheses of Industrially Important Commodity Chemicals, Pure Applied Chem., 2012, doi:10.1351/PAC-CON-11-06-12. (invited paper)

 

S.M. Mercer; J. Andraos, P.G. Jessop*;, Choosing the Greenest Synthesis: a multivariate metric green chemistry exercise, J. Chem. Educ. 2012, 89, 215-220.

 

L. Werner; A. Machara; B. Sullivan; I. Carrera; M. Moser; T. Hudlicky*, J. Andraos*, Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency, J. Org. Chem. 2011, 76, 10050-10067.

 

J. Andraos*, A Database Tool for Process Chemists and Chemical Engineers to Gauge the Material and Synthetic Efficiencies of Synthesis Plans to Industrially Important Targets, Pure Applied Chem. 2011, 83, 1361-1378. (invited paper)

 

J. Andraos*, Global Green Chemistry Metrics Analysis Algorithm and Spreadsheets:  Evaluation of the Material Efficiency Performances of Synthesis Plans for Oseltamivir Phosphate (Tamiflu) as a Test Case, Org. Process Res. Develop. 2009, 13, 161 – 185.

 

J. Andraos* and M. Sayed, On the Use of Green Metrics in the Undergraduate Organic Chemistry Lecture and Practicum to Assess the Material Efficiencies of Organic Reactions, J. Chem. Educ. 2007, 84, 1004 - 1011.

 

J. Andraos* and J. Izhakova, Perspectives on the Application of Green Chemistry Principles to Total Synthesis Design, Chimica Oggi/The International Journal of Industrial Chemistry and Biotechnology, November/December 2006, 24(6, Supp.), 31 - 36 (invited article).

 

J. Andraos*, On Using Tree Analysis to Quantify the Material, Input Energy, and Cost Efficiencies of Simple and Complex Synthesis Plans and Networks: toward a blueprint for quantitative total synthesis and green chemistry, Org. Process Research & Development 2006, 10, 212 - 240.

 

J. Andraos*, Unification of Reaction Metrics for Green Chemistry II:  Evaluation of Named Organic Reactions and Application to Reaction Discovery, Org. Process Research & Development. 2005, 9, 404 – 431.

 

J. Andraos*, Unification of Reaction Metrics for Green Chemistry:  Applications to Reaction Analysis, Org. Process Research & Development 2005, 9, 149 – 163.

 

Invited Addresses:

 

“Green Chemistry’s Impact on Research in and Teaching of Organic Synthesis”, University of Toronto, Toronto, CANADA, October 14, 2011

 

“A Database Tool for Process Chemists and Chemical Engineers to Gauge the Material and Synthetic Efficiencies of Synthesis Plans to Industrially Important Targets”, University of Ontario Institute of Technology, Oshawa, CANADA, October 13, 2010

 

“Perspectives on Teaching and Research in Green Chemistry”, University of Toronto, Toronto, CANADA, June 5, 2009

 

"Green Chemistry Metrics:  Application to Reaction and Synthesis Optimization", Apotex Pharmachem, Inc., April 22, 2008, Brantford, Ontario, CANADA

 

15th International Conference on Organic Process Research and Development, "Getting a Grip on Quantifying How Efficient a Synthesis Plan Is For a Given Target Product", San Diego, California, USA, January 8 - 10, 2007

 

"Getting a Grip on Quantifying How Efficient a Synthesis Plan Is For a Given Target Product", BioVerdant, Inc., San Diego, California, USA, January 11, 2007

 

“Green Chemistry Principles, Metrics and Industrial Implementation”

Three day training course given by Scientific Update LLP

(co-hosted with Dr. Peter L. Spargo)

Le Centre Sheraton, Montreal, June 19 – 21, 2007

 

Green Chemistry Metrics for Reaction and Synthesis Optimization, Merck & Co., Rahway, NJ, October 16, 2007

 

University of Toronto, Sigma-Xi invited address, "The "Algebra" of Organic Synthesis:  Green Chemistry and Synthesis Optimization", November 22, 2007

 

Green Chemistry and Engineering Education Workshop, Chemical Sciences Roundtable, "Green Chemistry:  Teaching and Research", National Academies, Washington, D.C., USA, November 7 - 8, 2005

 

 

Conferences:

 

J. Andraos, “Combinatorial Connectivity Analysis for the Discovery of New Multi-Component Reactions and Evaluation of their Likelihood to be “Green” Reactions”, presented at the Sustainability Chemistry Summit 2011:  From Lab to Market, September 16-18, 2011, Kingston, Ontario, CANADA

J. Andraos, "A Database Tool for Process Chemists and Chemical Engineers to Gauge the Material and Synthetic Efficiencies of Synthesis Plans to Industrially Important Targets", presented at the 3rd International IUPAC Conference on Green Chemistry, August 15 - 18, 2010, Ottawa, Ontario, CANADA

J. Andraos, "Challenges in Launching a University Level Green Chemistry Course for Students and Professional Chemists", presented at the 3rd International IUPAC Conference on Green Chemistry, August 15 - 18, 2010, Ottawa, Ontario, CANADA

J. Andraos, "Challenges in Launching a University Level Green Chemistry Course for Students and Professional Chemists", presented at the 93rd CSC Conference and Exhibition, May 29 - June 2, 2010, Toronto, Ontario, CANADA

J. Andraos, “Linking Synthetic Elegance, Material Efficiency, and Green Chemistry Principles for Synthesis Design and Analysis”, 90th CSC Conference and Exhibition, May 26 – 30, 2007, Winnipeg, Manitoba, CANADA

 

J. Andraos, "Getting a Grip on Quantifying How Efficient a Synthesis Plan is for a Given Target", presented at the International Symposium on Green Chemical Processes for Pharmaceuticals and Fine Chemicals, October 20 - 22, 2006, McGill University, Montreal, CANADA

 

J. Andraos and M. Sayed,  "On the Use of Green Metrics in the Undergraduate Organic Chemistry Practicum to Assess Material Efficiencies of Organic Reactions", presented at the 89th CSC Conference and Exhibition, May 27 - 31, 2006, Halifax, Nova Scotia, CANADA

 

J. Andraos, "On Using Tree Analysis to Quantify the Material, Input Energy, and Raw Material Cost Throughput Efficiencies of Simple and Complex Synthesis Plans and Networks", presented at the 89th CSC Conference and Exhibition, May 27 - 31, 2006, Halifax, Nova Scotia, CANADA (poster)

 

J. Andraos, "Unification of Reaction Metrics:  applications to reaction analysis and reaction discovery", presented at the Canada-US Joint Workshop on Innovative Chemistry in Clean Media, May 20 - 21, 2004, McGill University, Montreal, Quebec, CANADA (poster)

 

J. Andraos, “Assessing Worst Case Scenarios for Organic Reactions using Minimum Atom Economy and Maximum Environmental Impact Factor as Metrics, presented at the 39th IUPAC Congress and 86th CSC Conference and Exhibition, August 10 – 15, 2003, Ottawa, CANADA